News
27 Mar. 2026
Inserm CHAIR (tenure track position) opened in the Laboratoire d'Optique et Biosciences
An Inserm CHAIR (tenure track position) has just been opened in the Laboratoire d'Optique et Biosciences ( Inserm U1182) in École Polytechnique / Institut Polytechnique de Paris on “Development of nano-imaging methods for complex patho-physiological...
20 Mar. 2026
Revisiting the photocycle of a photoenzyme
A study conducted by teams from LOB, BIAM Cadarache and I2BC, combining multiple techniques including ADASOPS multi-scale transient infrared absorption spectroscopy, shows that, contrary to previous assumptions, at physiological temperature CO₂ is...
18 Mar. 2026
HDR Gael Latour
Félicitations à Gaël Latour pour la brillante soutenance de son Habilitation à Diriger des Recherches (HDR) intitulée : « Cornée, parchemin, vernis : la microscopie avancée comme outil d'investigation » !
19 Feb. 2026
Young Lobsters Day
Exciting science and discussion during the "Young Lobsters Day" Young Lobsters Day took place Thursday 19th February (full day). Please find the program attached. Presentation format: Postdocs, 3rd-year PhD students, and 2nd-year PhD students Interns and...
01 Feb. 2026
New publication in Nucleic Acids Research ”Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life"
Happy to share latest article on G-quadruplexes in Archaea: "Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life" published in Nucleic Acids Research Link in comments (paper in free access). We...
09 Jan. 2026
New publication in Nature Communication Biology, “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue”
A new paper on “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue” is published in Communications Biology, thanks to an exciting collaboration between the Laboratoire d'Optique et Biosciences (LOB) at Institut...
23 Oct. 2025
Femtosecond spectroscopy and molecular modeling uncover new insights into flavin photochemistry
Researchers from LOB Ecole Polytechnique and CEA Cadarache uncover the ultrafast photooxidation dynamics of the flavin cofactor in the natural photoenzyme - fatty acid photodecarboxylase (FAP). Using femtosecond transient absorption spectroscopy, the team...
19 Aug. 2025
Beyond the sequence: when DNA structure regulates genes
Researchers from the Laboratory for Optics and Biosciences participated in a study showing that certain three-dimensional structures of DNA, known as G-quadruplexes, play a key role in regulating gene expression in mammals. This work was published in...
13 May. 2025
Defects in DNA repair genes drive the emergence of antimicrobial resistance in Mycobacterium tuberculosis
The growing problem of antibiotic resistance worsens the social and economic burden of tuberculosis (TB) caused by Mycobacterium tuberculosis ( Mtb ). Using large-scale genomic analyses and genome editing, a LOB team has identified associations between...
07 May. 2025
Robin Kuhner , winner of Bertrand Pivin 2025 prize
Robin Kuhner, PhD student in the Laboratoire d’Optique et Biosciences was awwarded the 1 st Bertrand Pivin 2025 prize for his innovative project for health « SIMBAD » : Sensitive IMaging and optical detection for Biochemical Analysis and Diagnosis...
08 Mar. 2025
Operation Coquelicots at LOB #coquelicots #IWD2025
The LOB enthusiastically supports Operation Coquelicots and is decked out in red to make women scientists visible!