News

The Laboratory for Optics and Biosciences (LOB), founded in 2001 under the leadership of Jean-Louis Martin, celebrated its 25 th anniversary on June 18 at École Polytechnique. To mark the occasion, dozens of former doctoral and postdoctoral students from...

A new paper from the LOB microscopy unit on high-speed multiphoton light-sheet imaging has been published in Optica. We achieved kilohertz frame rates by enhancing the signal-to-photodamage ratio during live imaging. Two-photon light-sheet live imaging at...

Congratulation to Gael Latour's team. First paper from the LOB on OCT applied to the investigation of cultural heritage artifacts. We show the interest in imaging varnish layers, measuring their thicknesses and following conservation treatments based on...

An Inserm CHAIR (tenure track position) has just been opened in the Laboratoire d'Optique et Biosciences ( Inserm U1182) in École Polytechnique / Institut Polytechnique de Paris on “Development of nano-imaging methods for complex patho-physiological...

A study conducted by teams from LOB, BIAM Cadarache and I2BC, combining multiple techniques including ADASOPS multi-scale transient infrared absorption spectroscopy, shows that, contrary to previous assumptions, at physiological temperature CO₂ is...

Félicitations à Gaël Latour pour la brillante soutenance de son Habilitation à Diriger des Recherches (HDR) intitulée : « Cornée, parchemin, vernis : la microscopie avancée comme outil d'investigation » !

A big congratulations to Kate Sorg, third prize IP Paris My Thesis in 180 Seconds She will take part in the regional final of the MT 180 competition, which will take place on April 16, 2026, at La Terrasse in Gif-sur-Yvette. 2026 Winners The jury...

Exciting science and discussion during the "Young Lobsters Day" Young Lobsters Day took place Thursday 19th February (full day). Please find the program attached. Presentation format: Postdocs, 3rd-year PhD students, and 2nd-year PhD students Interns and...

Happy to share latest article on G-quadruplexes in Archaea: "Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life" published in Nucleic Acids Research Link in comments (paper in free access). We...

A new paper on “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue” is published in Communications Biology, thanks to an exciting collaboration between the Laboratoire d'Optique et Biosciences (LOB) at Institut...

Researchers from LOB Ecole Polytechnique and CEA Cadarache uncover the ultrafast photooxidation dynamics of the flavin cofactor in the natural photoenzyme - fatty acid photodecarboxylase (FAP). Using femtosecond transient absorption spectroscopy, the team...

Researchers from the Laboratory for Optics and Biosciences participated in a study showing that certain three-dimensional structures of DNA, known as G-quadruplexes, play a key role in regulating gene expression in mammals. This work was published in...