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Inserm CHAIR (tenure track position) opened in the Laboratoire d'Optique et Biosciences
27 Mar. 2026

Inserm CHAIR (tenure track position) opened in the Laboratoire d'Optique et Biosciences

An Inserm CHAIR (tenure track position) has just been opened in the Laboratoire d'Optique et Biosciences ( Inserm U1182) in École Polytechnique / Institut Polytechnique de Paris on “Development of nano-imaging methods for complex patho-physiological...
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Revisiting the photocycle of a photoenzyme
20 Mar. 2026

Revisiting the photocycle of a photoenzyme

A study conducted by teams from LOB, BIAM Cadarache and I2BC, combining multiple techniques including ADASOPS multi-scale transient infrared absorption spectroscopy, shows that, contrary to previous assumptions, at physiological temperature CO₂ is...
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HDR Gael Latour
18 Mar. 2026

HDR Gael Latour

Félicitations à Gaël Latour pour la brillante soutenance de son Habilitation à Diriger des Recherches (HDR) intitulée : « Cornée, parchemin, vernis : la microscopie avancée comme outil d'investigation » !
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New Prize
12 Mar. 2026

New Prize

A big congratulations to Kate Sorg, third prize IP Paris My Thesis in 180 Seconds She will take part in the regional final of the MT 180 competition, which will take place on April 16, 2026, at La Terrasse in Gif-sur-Yvette. 2026 Winners The jury...
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Young Lobsters Day
19 Feb. 2026

Young Lobsters Day

Exciting science and discussion during the "Young Lobsters Day" Young Lobsters Day took place Thursday 19th February (full day). Please find the program attached. Presentation format: Postdocs, 3rd-year PhD students, and 2nd-year PhD students Interns and...
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New publication in Nucleic Acids Research ”Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life"
01 Feb. 2026

New publication in Nucleic Acids Research ”Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life"

Happy to share latest article on G-quadruplexes in Archaea: "Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life" published in Nucleic Acids Research Link in comments (paper in free access). We...
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New publication in Nature Communication Biology, “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue”
09 Jan. 2026

New publication in Nature Communication Biology, “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue”

A new paper on “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue” is published in Communications Biology, thanks to an exciting collaboration between the Laboratoire d'Optique et Biosciences (LOB) at Institut...
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Femtosecond spectroscopy and molecular modeling uncover new insights into flavin photochemistry
23 Oct. 2025

Femtosecond spectroscopy and molecular modeling uncover new insights into flavin photochemistry

Researchers from LOB Ecole Polytechnique and CEA Cadarache uncover the ultrafast photooxidation dynamics of the flavin cofactor in the natural photoenzyme - fatty acid photodecarboxylase (FAP). Using femtosecond transient absorption spectroscopy, the team...
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Beyond the sequence: when DNA structure regulates genes
19 Aug. 2025

Beyond the sequence: when DNA structure regulates genes

Researchers from the Laboratory for Optics and Biosciences participated in a study showing that certain three-dimensional structures of DNA, known as G-quadruplexes, play a key role in regulating gene expression in mammals. This work was published in...
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Defects in DNA repair genes drive the emergence of antimicrobial resistance in Mycobacterium tuberculosis
13 May. 2025

Defects in DNA repair genes drive the emergence of antimicrobial resistance in Mycobacterium tuberculosis

The growing problem of antibiotic resistance worsens the social and economic burden of tuberculosis (TB) caused by Mycobacterium tuberculosis ( Mtb ). Using large-scale genomic analyses and genome editing, a LOB team has identified associations between...
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Robin Kuhner , winner of Bertrand Pivin 2025 prize
07 May. 2025

Robin Kuhner , winner of Bertrand Pivin 2025 prize

Robin Kuhner, PhD student in the Laboratoire d’Optique et Biosciences was awwarded the 1 st Bertrand Pivin 2025 prize for his innovative project for health « SIMBAD » : Sensitive IMaging and optical detection for Biochemical Analysis and Diagnosis...
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Operation Coquelicots at LOB #coquelicots #IWD2025
08 Mar. 2025

Operation Coquelicots at LOB #coquelicots #IWD2025

The LOB enthusiastically supports Operation Coquelicots and is decked out in red to make women scientists visible!
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