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NO receptors and sensors
Staff:Isabelle Lamarre-JouenneJean Christophe LambryMichel NégrerieResearch topics: Selected publications:
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PhD & Master internships
PhD and Master internship proposals are generally advertized between October and March. For inquiries about the current possibilities, you can also contact LOB scientists.Master/PhD proposals 2026:Brain-wide mapping with color multiphoton microscopy [see project page] (E. Beaurepaire, P. Mahou)Past…
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Polytechnique bioimaging facility / Morphoscope
The Morphoscope / Polytechnique Bioimaging Facility is hosted and operated by the Laboratory for Optics & Biosciences at Ecole Polytechnique.
Morphoscope is an optical microscopy platform with emphasis on methodological innovation, resulting from a major equipment investment grant (Equipex M…
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Postdocs
Postdoc opportunities:(10/2024) Postdoc position: Modeling/simulation in developmental neurobiology. The Advanced Microscopy Group is looking for a postdoctoral researcher to work on computer simulations of the development of connections in the medial nucleus of the trapezoid body (MNTB), a mouse a…
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Presentation of the laboratory
Founded in 2001, the Laboratory of Optics and Biosciences (LOB) is affiliated with the French Institute of Health and Medical Research (INSERM), the French National Centre for Scientific Research (CNRS), and Ecole Polytechnique. The Laboratory brings together scientists with expertise in …
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Protein and DNA folding dynamics probed by time-resolved circular dichroism
Staff:Pascale ChangenetFrancois HachePost-doc:Vangelis BalanikasResearch topics:In addition to their three-dimensional structure, the dynamical properties of biomolecules play a key role in their functions. During their folding, they explore a wide range of conformations, which can be difficult to …
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Replication in archaea
StaffRoxane Lestini / Ecole polytechniqueNicolas Olivier / CNRSStéphane Duigou / CNRSLionel Guittat / Université Sorbonne Paris-NordCaroline l'Hermitte-Stead / INSERMTom MARIOTTE / Post-docKate Sorg / PhD Internship proposals / Propositions de stage :Please do not hesitate to contact us if you…
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Revisiting the photocycle of a photoenzyme
A study conducted by teams from LOB, BIAM Cadarache and I2BC, combining multiple techniques including ADASOPS multi-scale transient infrared absorption spectroscopy, shows that, contrary to previous assumptions, at physiological temperature CO₂ is converted into an intermediate other than bicarbona…
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Robin Kuhner , winner of Bertrand Pivin 2025 prize
Robin Kuhner, PhD student in the Laboratoire d’Optique et Biosciences was awwarded the 1st Bertrand Pivin 2025 prize for his innovative project for health « SIMBAD » : Sensitive IMaging and optical detection for Biochemical Analysis and Diagnosis.Congratulations !
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Roxane Lestini
Professor, Ecole polytechniqueVice-president, Biology departmentRoom : 84-2012roxane.lestini at polytechnique.edu Research interestReplication dynamics and Replication stress response in ArchaeaG-quadruplexes and replication in Archaea https://orcid.org/0000-0001-7377-4734TeachingM…
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